I don't think you can turn off all the menus/toolbars and lock them. See http://www.adobe.com/devnet-docs/acrobatetk/tools/PrefRef/Windows/inde x.html and look up Toolbar Customization. You could deploy those settings via the Wizard's Registry feature.
I believe that the Fit to Window answer can probably be found in this forum post: http://forums.adobe.com/thread/787856.
hth,
Ben