You can only disable the items via reg prefs as documented in the Wizard Guide and the Pref Ref: http://www.adobe.com/devnet-docs/acrobatetk/.
The reg pref do not disable the EchoSign items under the file menu, splash page, and perhaps elsewhere. This will probably change in upcoming releases.
With respect to the Tools Panels on the right, muck around with creating custom toolbars and see if you get what you want (if you haven't already).
hth,
Ben