We also use SCCM to deploy, You need to find out whats going on at the package level
Try using the MSI logs to help workout what's going on example
Msiexec /I "AcroRead.msi" /QN TRANSFORMS="Adobe_ReaderXI_11.0_1.0.mst" /L* "C:\Windows\SOE\Logs\Adobe_ReaderXI_11.0_1.0_Install.log"
